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miRNA

저작시기 2007.12 |등록일 2017.05.05 파워포인트파일MS 파워포인트 (ppt) | 17페이지 | 가격 1,000원

목차

1. What is microRNA (miRNA)?
2. What is microRNA (miRNA)? (Con’t)
3. miRNAs involved in vascular biology
4. miRNA array (cLDL treated HUVEC)

본문내용

What is microRNA (miRNA)?
• Non-coding small interfering endogenous RNAs
• First discovered in Caenorhabditis elegans in 1993
• A fundamental component of the regulatory system of gene expression
> 500 miRNAs in the human genome
• Functions in stress resistance, in metbolism, etc…

What is microRNA (miRNA)? (Con’t)
• Base pairing with complementary sequences in the 3’ UTRs
• Functions largely unknown.
• Location overlaped with known protein coding or noncoding genes.
> 3% of the human genome.
• Regulate~ 30% of the protein-coding genes

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