1. Keir AK 외 4명(2014). Co-infusion of dextrose-containing fluids and red blood cells does not adversely affect in vitro red blood cell quality. Transfusion. 2014 Aug;54(8):2068-76. doi: 10.1111/trf.12618. Epub 2014 Mar 28.
Transfusion guidelines advise against coinfusing red blood cells (RBCs) with solutions other than 0.9% saline. We evaluated the impact of coinfusion with dextrose-containing fluids (DW) on markers of RBC quality.
STUDY DESIGN AND METHODS:
A pool-and-split design was used to allow conditions to be tested on each pool within 2 hours of irradiation. Three pools at each storage age (5, 14, and 21 days) were created for each phase. In Phase 1, samples were infused through a neonatal transfusion apparatus alone or with treatment solutions: D5W, D10W, D5W/0.2% saline, and 0.9% saline. In Phase 2, samples were incubated alone or in a 1:1 ratio with treatment solutions and tested after 5, 30, and 180 minutes.