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골다공증 최신치료

저작시기 2012.05 |등록일 2012.05.22 파워포인트파일MS 파워포인트 (pptx) | 57페이지 | 가격 2,500원

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2012 update 된 골다공증 최신치료입니다

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AbstractOsteoporosis is consequence of an unbalanced bone remodeling process
decrease in bone density, alterations in bone microarchitecture, and ultimately Fractures.
predominantly a disease of aging, affecting particularly postmenopausal women, but also older men

Abstract
antiresorptive drugs
bisphosphonates, denosumab, calcitonin, estrogens or selective estrogen receptor modulators
they lead to a low turnover state -> decrease in bone-remodeling activity
alternative class of osteoporosis drugs -> bone anabolics
bone anabolics
osteoanabolic pathways
PTH : the only anabolic drug currently on the market
canonical Wnt signaling : through inhibition of the endogenous inhibitors (sclerostin and dickkopf1)

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