For 24 years (1878-1902) he was Editor of the Revue Scientifique, and from 1917 he was co-editor of the Journal de Physiologie et de Pathologie Generale.
He has published papers on physiology, physiological chemistry, experimental pathology, and pathological psychology and numerous researches all done in the physiological laboratory of the Faculty of Medicine, Paris.
In physiology, he worked out the mechanism of the thermoregulation in homoiothermic animals.
But, before his researches (1885-1895) on polypnea and shivering due to temperature little was known about the methods by which animals deprived of cutaneous transpiration can guard against overheating and how chilled animals can warm themselves again.
In experimental therapeutics Richet showed that the blood of animals vaccinated against an infection protects against infection
Applying this principle to tuberculosis, he did the first injection done in man
(Dec. 6, 1890).