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저작시기 2008.03 |등록일 2011.03.19 파워포인트파일MS 파워포인트 (pptx) | 23페이지 | 가격 1,000원

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Moving Out: Invasion and Metastasis
1. Extracellular proteases play key roles in invasiveness
The epithelial-mesenchymal transition (EMT) represents a complex biological program that enables cancer cells to acquire the atttributes of invasiveness and motility.
matrix degradaing enzyme→cell adhesion→cell motility
The most important effectors of these complex changes are the matirx metallo-proteinases (MMPs)
ts of the extracellular matrix (ECM)
1. Extracellular proteases play key roles in invasiveness
1. Extracellular proteases play key roles in invasiveness
Included among the ECM components that are cleaved by MMPs are fibronectin, tenascin, laminin, collagens, and
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