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Fibrous dysplasia

저작시기 2009.11 |등록일 2009.12.27 파워포인트파일MS 파워포인트 (ppt) | 24페이지 | 가격 1,500원

소개글

Fibrous dysplasia에 대한 정리입니다.

Malignant change에 대한 내용도 함께 정리 되어있습니다.

bone tumor 교과서와 최신 저널을 참고로 만들었어요. (참고 자료 확인하세요)

목차

1. Case
2. Definition
3. Clinical features
4. Skeletal distribution
5. Radiologic features
6. Treatment
7. Malignant transformation

본문내용

7. Malignant transformation

FD has the potential for malignant change.

Malignant change in FD is very rare

0.5%: monostotic FD /4%:McCune–Albright SD

Common type:
Osteosarcoma(~70%)
Fibrosarcoma(~20%)
Chondrosarcoma(~10%)
Malignant fibrous histiocytoma (~4%)

Risk factors of malignant change
Polyostotic FD
McCune–Albright SD
Mazabraud SD
Prior radiation exposure

Rapid increasing pain without trauma
Progressed weakness, deformity
Significant change in radiologic appearance

참고 자료

1. Riddle NMD et al. Dedifferentiated chondrosarcoma arising in fibrous dysplasia: A case report and review of the current literature. Path LabMed Int. 5:1-6, 2009.
2. Hoshi M et al. Malignant change secondary to fibrous dysplasia. Int J Clin Oncol. 11:229-235, 2006.
3. Bone Tumors. Vol. 2. Clinical, Radiologic, and Pathologic Correlations. Joseph M. Mirra. Lea & Febiger. 1989.
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