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[의학약학]B형 간염 바이러스의 특징 및 치료 전략

저작시기 2007.05 |등록일 2007.06.04 워드파일MS 워드 (doc) | 11페이지 | 가격 1,500원

소개글

B형 간염 바이러스의 생리학적, 유전학적, 분자생물학적 특성 및 B형 간염 질환의 특성, 치료전략에 대한 내용으로 영문으로 작성된 학교 과제 리포트입니다.

목차

1. What is Hepatitis B virus?
2. Transmission of Hepatitis B
3. Structure of Hepatitis B virus
4. The genome of Hepatitis B virus
5. Hepatitis B antigen
6. Life cycle of hepatitis B virus
7. Structure of HBV core protein and capsid
8. HBV surface protein
9. HBV X protein
10. Immunopathgenesis of HBV infection
11. Therapeutic approaches and response of HBV
12. Mutation of HBV
13. Control of HBV
14. Clinical approach to treat HBV

본문내용

2. Transmission of Hepatitis B

?Vertical transmission
From mother to child during childbirth
90% risk of passing the infection to offspring if mother is positive for HBeAg
20% risk of passing the infection to offspring if mother is positive for HBsAg (surface antigen)
In highly prevalence area (South East Asia), vertical transmission is most common
?Unprotected sexual contact
16~40% of unimmunized people will be infected through sexual contact
?Blood transfusion
?Re-use of contaminated needles and syringes


3. Structure of Hepatitis B virus

?Diameter of 42nm, originally called the Dane particle
?The particle consists of 7nm outer shell and 27nm inner core, contains partially dsDNA molecule
?Outer envelop contains three types of Hepatitis B surface proteins (L, M and S)
?Inner nucleocapsid is made up of 180 Hepatitis B core proteins in an icosahedral arrangement
?Nucleocapsid contains at least one Hepatitis B polymerase protein (P) along with the HBV genome

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