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IgA nephropathy

저작시기 2006.01 |등록일 2007.01.01 한글파일한글 (hwp) | 8페이지 | 가격 500원

소개글

IgA Nephropathy에 관한 review글 입니다.

목차

1. Introduction
2. Dermographic features
3. Incidence
4. Cause and Genetic Factors
5. Pathogenesis
6. Pathology
7. Clinical Features
8. Outcome
9. Treatment
10. Renal Transplantation
11. Differential Diagnosis

본문내용

1. Introduction
IgA Nephropathy (IgAN)
- relatively newly recongnized disease
- first described by Berger and Hinglais in 1968
- most common form of primary glomerulonephritis throughout the world
- main cause of end-stage renal disease in patients with primary glomerular disease who
require renal-replacement therapy
Primary IgA Nephropathy
- immune-complex-mediated glomerulonephritis defined immunohistologically
- presence of glomerular IgA deposits accompanied by a variety of histopathologic lesions
* Other disease associated with glomerular IgA deposits
- most common : Schonlein-Henoch purpura

2. Dermographic features
- at any age, most commonly with clinical onset in the 2nd and 3rd decades of life
- male:female ratio → less than 2:1 in Japan, 6:1 in northern Europe and the United States
- more prone for whties and Asians

3. Incidence
- In Europe, 15~40 new cases per million population per year
- In United States, 5(1975~79)→12 cases(1990~94) per million population per year
- prevalence rate
: 20~40%, highest in Asia, Australia, Finland and southern Europe
: much lower in USA(2~10%), United Kingdom, Canada

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