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[소아과학] 신생아 황달(Jaundice and Hyperbilirubinemia in the Newborn)

저작시기 2005.05 |등록일 2005.08.04 한글파일한컴오피스 (hwp) | 7페이지 | 가격 500원

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* Hyperbilirubinemia
Etiology
Clinical Manifestations
Differential Diagnosis
Pathologic Hyperbilirubinemia
Jaundice Associated With Breast-Feeding
Treatment
ABO incompatibility

본문내용

Hyperbilirubinemia
1) common and in most cases benign problem in neonates
2) untreated severe
(1) indirect hyperbilirubinemia : potentially neurotoxic
(2) conjugated-direct hyperbilirubinemia : a serious illness
3) 생후 1st wk에 60% of term infants
80% of preterm infants

ETIOLOGY.

1) Unconjugated hyperbilirubinemia
(1) increases the load of bilirubin to be metabolized by the liver
ⓐ hemolytic anemias
ⓑ shortened red cell life due to immaturity or to transfused cells
ⓒ increased enterohepatic circulation
ⓓ infection
(2) damage or reduce the activity of the transferase enzyme
ⓐ genetic deficiency
ⓑ hypoxia
ⓒ infection
ⓓ possibly hypothermia
ⓔ thyroid deficiency
(3) compete for or block the transferase enzyme
ⓐ drugs and other substances requiring glucuronic acid conjugation for excretion
(4) leads to an absence of or decreased amounts of the enzyme or to reduction of bilirubin uptake by the liver cells
ⓐ genetic defect
ⓑ prematurity

참고 자료

Nelson Textbook of pediatrics
소아과학 홍창의편
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