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Prevalence increase with age, higher in developing country, among lower socioeconomic strata of the more developed nations
Saliva, breast milk, cervical and vaginal secretions, urine, semen, stools and blood
Direct person to person contact: close or intimate contact
Indirect transmission: possible via contaminated fomites
Incidence of congenital infection
0.2~2.4% of all live birth
Consequence of primary and recurrent maternal infection
The rise for fetal infection is greatest with maternal primary CMV infection
Incidence of perinatal transmission
10~60% by 6 month of age
By genital tract secretion at delivery and breast milk