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ACUTE MYELOGENOUS LEUKEMIA

등록일 2000.10.08 한글파일한글 (hwp) | 8페이지 | 가격 1,000원

목차

Introduction
Etiology and Epidemiology
Natural History
Teatment of Newly Diagnosed AML
Treatment of Relapsed and Refractory AML

본문내용

Introduction
* The proliferation of malignant myeloblasts and other immature myelocytic cell
* leukemic cell 이 BM infiltration hematopoiesis impairment
anemia, granulocytopenia,thrombocytopenia
* Untreated rapidly fatal
* Mean survival- less than 2 month
* Recent therapy;
① Intensive chemotherapy
② Autologous or allogenic bone marrow transplantation

Etiology and Epidemiology
* Incidence
5/10,000 in U.S.A.
no seasonal variation
* median age of onset; 50 yrs
* Etiology
① Hereditary disease; Down, Bloom, Klinefelter and Wiskott-Aldrich syndrome
② Ionizing radiation
③ Benzene, Toluene
④ Chloramphenicol
⑤ Several acquired disease;
myeloproliferative disorders, multiple myeloma, Hodgkin's disease and
non-Hodgkin's disease
⑥ Alkylating agent
Natural History

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