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[의학]Aspirin - Ulceration

등록일 2000.06.21 한글파일한글 (hwp) | 1페이지 | 가격 500원

목차

가. 관련질환
나. mechanisms of ulceration
다. High risk factors
라. 예방(reduce risk)

본문내용

가. 관련질환
(가) GU(10~30%), DU(2~20%) ꀴ hemorrhagic erosive gastropathy.
bleeding : 4ml/d가 stool에서 (NL : 1ml/d)
poor correlation : symptoms - chronic ulcers.
(나) small intestinal and colonic ulceration and strictures
(다) exacerbations of CD and UC
나. mechanisms of ulceration
(가) directly toxic to the gastric mucosa,
(나) inhibiting PG synthesis : mucosal PG ꀶ
1) interrupting the gastric mucosal barrier
ꀶ gastric mucus secretion, bicarbonate secretion
2) ꀵ back-diffusion of hydrogen ions ➜ increase gastric acid secretion.
3) impairs epithelial cell replacement after injury.
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